ArtemisiA was formed in November 2006 by Vito Flebus and Anna Ballarin, driven by a shared desire to create something original and true to their own musical vision. From the very beginning, the band set out to follow a path of its own, deliberately keeping a distance from the more mainstream side of the Italian music scene. The original line-up featured Anna on vocals, Vito on guitar, Fabio Corsi on bass, and Matteo Macuz on drums.

In 2007, shortly after signing their first record deal, ArtemisiA released their self-titled debut album, recorded at the studio of Andrea Rigonat, longtime guitarist for Elisa Toffoli. The single “L'aliante” received airplay on stations including Radio Capodistria and LatteMiele, while the album was accompanied by the band’s first music video, “Artemisia”, directed by visual artist Isabella Pers. Alongside an intense live schedule, ArtemisiA also took part in numerous festivals and competitions, often finishing among the top acts.

Their 2010 release, “Gocce d'assenzio”, marked an important turning point, bringing the band to the attention of the music press. The album was met with strong reviews from respected publications such as Rockerilla and Hard n' Heavy.

Between 2010 and 2011, the line-up changed, with Matteo leaving first and Fabio soon after to pursue other projects. Anna and Vito continued the band’s journey with drummer Gabriele “Hammerdonk” Gustin and bassist Ivano Bello. This new line-up led to the release of “Stati Alterati di Coscienza” in 2013, an album warmly welcomed by both the specialist press and magazines such as Guitar Club and Rockhard. Its lead single, “La strega di Port'Alba”, was accompanied by a video directed by Erik Canciani, which reached the finals of the Michel Gondry FilmFestival in the music video category.

In 2016, the band recorded their fourth album at Blasig Studio, with special contributions from maestro Carlo Marzaroli on violin and maestro Massimo Devitor, who conducted the Gospel Soul Circus choir on selected tracks.

Following a label change, ArtemisiA released “Rito apotropaico” in early 2017, preceded by the video for “Tavola antica”, directed by Andrea Cerovac. That same year, Elettra Medessi joined the band as backing vocalist and second voice, allowing the layered vocal arrangements of the studio recordings to be brought more fully into the live setting. Live performance has always been central to ArtemisiA’s identity, and it is on stage that the band’s earthy, powerful sound finds its fullest expression.

The intense touring cycle that followed led to the release of the live album “Anime inquiete” in 2019. Alongside newer material, the record also captured a kind of best-of selection, bringing together some of the songs that had come to define the band’s first ten years.

Towards the end of 2019 and in the early months of the ill-fated 2020, ArtemisiA entered the studio to record what would become their fifth studio album. Titled “Derealizzazione sintomatica”, the album was released on January 22, 2021, once again through Alessio Ligorio’s Onde Roar Records. It featured a special guest appearance by former Timoria frontman Omar Pedrini, who duets with Anna on “Fata verde”, along with several other guest musicians who further enriched the record. The first single chosen to introduce the album was “Ombre della mente”, released on December 4, 2020, together with a video directed by Marco Iacobelli in collaboration with Diego “Imakarum” Caponetto. In July 2021, keyboardist Ulisse Tonon joined the band, and in the months that followed ArtemisiA appeared at the Fosar festival and on the Rai Radio 1 programme “Rock Revolution”.

On December 16, 2021, the band released the video for “Fata verde”, the second single from “Derealizzazione sintomatica”, directed by Diego Caponetto and once again featuring Omar Pedrini on vocals.

In 2022, keyboardist Ezio Turus joined the ArtemisiA line-up, replacing Ulisse Tonon. On September 3, 2023, the band released the video for “Ladro d'anime”, the third single taken from “Derealizzazione Sintomatica”.

In 2026, ArtemisiA signed with Volcano Records for the release of their seventh album